Monthly Archives: February 2017

Selenium Vit C and Dr Porter

I recently had an exchange with Dr Mark Porter. I took exception to his recent article in the Times which more or less trashed the idea of people using Vitamin supp’s to combat disease. I challenged this firstly on the Vit C front (but also on others) and I am glad I did because you always learn something when you talk to people with opposing views. It gets you off your backside to investigate. Dr Porter kindly replied and sent me a link to a meta analysis that essentially showed that no Vitamin was beneficial in a statistically significant way in relation to heart disease amongst other diseases, when supplemented, although selenium came pretty close. A meta analysis by the way is when a researcher takes all the research papers done on a topic and then pools together all the results to form one overall result. It also enables them to filter out badly designed studies. I decided to dig a little deeper into the meta analysis and in particular the heart disease and Vit C category. I am convinced that Vit C can impact Lp(a) and hence CVD. When I looked closely at the 7 studies forming the meta analysis on Vit C I noticed that they had weighted them. Now I forget the exact method of weighting but it sure wasn’t based on dosage because one study was weighted with 78%!! of the overall value of the analysis and this study only used 250mg of Vit C per day on people with heart disease. This study came out as pretty much neutral on Vit C and given that the overall score OR was 0.99 for Vit C (the more below 1 the better) you can see that this one study had massive or should I say 78% effect on the overall outcome of the meta analysis. As I said to Dr Porter, Linus Pauling would have laughed at 250mg even for healthy subjects. Incidently getting back to Selenium there is an interesting Swedish study that showed in subjects over 60 that a combo of Selenium and Coq10 slashed risk by 50%.

Footnote – Just discovered that Dr Porter has recently adopted a similar attitude to Carb’s as myself

https://web.archive.org/web/20160526203646/http://drmarkporter.co.uk/low-carb-diet-my-6-week-experiment-to-see-how-cutting-back-on-carbs-impacted-on-my-blood-cholesterol-lipid-profile

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Japanese Total to HDL ratio

Over the last three decades total cholesterol has risen in japan but Heart disease has dropped. The linked report suggests that the reason for this may be their higher than average HDL and healthy Total to HDL ratios. The other interesting aspect of the report was the differences logged in Dietary intake between the Japanese, American and Australian subjects monitored. The main differences were

Fats significantly lower in Japanese
Fish and sea food much higher in Japanese
Eggs much higher in Japanese
Tofu and related products much higher in Japanese
Mushrooms much higher in Japanese
Fruits higher in Japanese

Cereals
Potatoes
Meats
Milk
Vegetables

were pretty much the same across the three countries.

Report http://circ.ahajournals.org/content/96/9/2830

Magnesium and CVD

With soil being continually depleted of magnesium we are getting less and less in our food supply. The research list connecting Magnesium deficiency and heart disease is long. here are just a few

https://www.ncbi.nlm.nih.gov/pubmed/21849940

https://www.ncbi.nlm.nih.gov/pubmed/24436973

https://www.ncbi.nlm.nih.gov/pubmed/26729158

https://www.ncbi.nlm.nih.gov/pubmed/26802105

Lazy solution – Eat a handful of almonds and or pumpkin seeds with your breakfast