LDL Particle Size Test Results

Having finally found a UK source for an LDL particle size test I got my results back today. There were other marker results in the test and it was a mixture of mainly good news but some not so good. The results were as follows Total Cholesterol 5.64 LDL Cholesterol 3.08 HDL 2.17 Triglycerides 0.87 LDL paricle count 1,131 HDL partcile count 30.2 LDL Size 21.1 (means large pattern A) LP(a) 0.82 CRP 0.52 LpPLA2 210 Fibrinogen 9.1 Homocysteine 23.5 The good news is that the LDL size was big and fluffy and not small and dense. Most other markers were all in acceptable range for the marker with the exception of Total LDL (for those who still think this marker is predictive), LpPLA (too high) and Homocysteine (too high). Homocysteine was very much on the high side with the acceptable range being 3.7 to 10.4. The jury seems to be out a little on this factor, some people seem unconvinced that it is a responsible factor for heart disease whilst others are. It is produced from methionine and has a genetic influence. Kidney problems can also elevate this factor so the way forward would seem to be centred around keeping ones kidneys flushed with water and reducing high methionine foods such as meat (not really applicable in my case) and Brazil nuts (applicable in my case). PLA2 is an enzyme detected in the blood when someone has plaque build up in the arteries. This one might prove a little harder to crack.

There are some useful comments below on the use of Vit B6, B12 and Folate for lowering Homocysteine and a useful link here



17 thoughts on “LDL Particle Size Test Results

  1. Homocysteine is quite out of whack!!!
    Fortunately it can be brought down with the simultaneous usage of three B vitamins in the adequate form:

    Vitamin B9 as L-methylfolate (Metafolin®)
    Vitamin B6 as Pyridoxine HCL (or better, P-5-P its active form)
    Vitamin B12 as Methylcobalamin

  2. Yes you are correct. I have already begun a daily Multi Vit B supplement which includes B6 B12 and Folate. Hopefully this will have the desired effect but I wont know until I recheck in a couple of months

  3. It’s very important that B9 is in the L-methylfolate form rather than regular Folic Acid, and B12 as methylcobalamin rather than the cheaper cyanocobalamin.

    That’s because the “methyl” part of the molecules is precisely what does the dirty job of turning homocysteine to methionine.

    1. I will have to check this out but I suspect that the ones I am using, bought from a supplement shop in the HIgh street in the UK may not be up to scratch. Thanks for this information Yosako. Where are you based by the way ?

    2. Just checked the labels and the B12 is indeed the cheaper variety you mentioned. Does not state what the Folic Acid is so I suspect its bog standard. I will go in search of the smarter variety you mention. Thanks for the heads up on this angle

      1. About homocysteine:

        And there is some info about forms of folate:

        Solgar brand has both Folate as Metafolin, vit. B6 (P-5-P form is optional: if you’re B2 replete, regular pyridoxine HCl should work) and B12 as Methylcobalamin.

        There is also another form of folate under the trade name Quatrefolic® which appears to be as well absorbed as Metafolin®.
        If you’re in the UK, you have it there: http://www.healthmonthly.co.uk/

    1. Blue Horizon run the test, google them. They may not yet list the test on their web site but email or call them and ask for details as its a new test they have just included. Most of their blood tests involve a trip to a local Spires hospital but with this one you have to go to a London clinic to give the blood. They send you a kit in the post, you take this along to London and they take the sample. Results come through via email about 2 weeks later. I am glad I did because I was unaware that they would test for Homocysteine and I was equally unaware that mine was high.

      1. I’ve had a look on the Blue Horizon web-site and can’t identify the test you are talking about. Before I give them a ring, do you have the name Blue Horizon use for the test you are describing. Thanks.

      2. Hi, its a new test they have only just introduced and at the time I had it there was no label or test name for it. If you ring them and ask they will know what you are after. It comes with a few other markers too eg homocysteine

    1. Vitamin B route is the road to go.
      NAC is more of a short term fix as it’s commonly used for bronchitis which tends to last one or a couple weeks at most, while vitamin B multis are meant to be taken for several months.

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